Long QT syndrome 1 is an autosomal dominant disorder caused by mutations of the KCNQ1 gene.
| 1. |
Tye KH et al. (1980) Survival following spontaneous ventricular flutter-fibrillation associated with QT syndrome. Documentation during ambulatory monitoring.
|
| 2. |
Weitkamp LR et al. (1994) Analysis of HLA and disease susceptibility: chromosome 6 genes and sex influence long-QT phenotype.
|
| 3. |
Tanaka T et al. (1994) Genetic linkage analyses of Romano-Ward syndrome (RWS) in 13 Japanese families.
|
| 4. |
Ko YL et al. (1994) No evidence for linkage of long QT syndrome and chromosome 11p15.5 markers in a Chinese family: evidence for genetic heterogeneity.
|
| 5. |
Jiang C et al. (1994) Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity.
|
| 6. |
Roy N et al. (1994) Exclusion of HRAS from long QT locus.
|
| 7. |
Mitsutake A et al. (1981) Usefulness of the Valsalva maneuver in management of the long QT syndrome.
|
| 8. |
DeSilvey DL et al. (1980) Primidone in the treatment of the long QT syndrome: QT shortening and ventricular arrhythmia suppression.
|
| 9. |
Di Segni E et al. (1980) Permanent overdrive pacing for the suppression of recurrent ventricular tachycardia in a newborn with long QT syndrome.
|
| 10. |
Towbin JA et al. (1994) Evidence of genetic heterogeneity in Romano-Ward long QT syndrome. Analysis of 23 families.
|
| 11. |
Flugelman MY et al. (1982) Congenital prolongation of Q-T interval: a family study of three generations.
|
| 12. |
Milne JR et al. (1982) The long QT syndrome; effects of drugs and left stellate ganglion block.
|
| 13. |
Itoh S et al. (1982) A study of the inheritance pattern of Romano-Ward syndrome. Prolonged Q-T interval, syncope, and sudden death.
|
| 14. |
Garza LA et al. (1970) Heritable Q-T prolongation without deafness.
|
| 15. |
Moss AJ et al. (1971) Unilateral cervicothoracic sympathetic ganglionectomy for the treatment of long QT interval syndrome.
|
| 16. |
Singer PA et al. (1974) Familial Q-T prolongation syndrome. Convulsive seizures and paroxysmal ventricular fibrillation.
|
| 17. |
van der Straaten PJ et al. (1973) A family with heritable electrocardiographic QT-prolongation.
|
| 18. |
Itoh T et al. (2001) Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome.
|
| 19. |
None (1993) Response.
|
| 20. |
Gouas L et al. (2005) Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population.
|
| 21. |
None (1965) CONGENITAL CARDIAC ARRHYTHMIA.
|
| 22. |
GAMSTORP I et al. (1964) CONGENITAL CARDIAC ARRHYTHMIA.
|
| 23. |
Priori SG et al. (2003) Risk stratification in the long-QT syndrome.
|
| 24. |
None (2003) The long-QT syndrome--bedside to bench to bedside.
|
| 25. |
Kimbrough J et al. (2001) Clinical implications for affected parents and siblings of probands with long-QT syndrome.
|
| 26. |
Miller MD et al. (2001) Diagnostic accuracy of screening electrocardiograms in long QT syndrome I.
|
| 27. |
Priori SG et al. (1999) Low penetrance in the long-QT syndrome: clinical impact.
|
| 28. |
Locati EH et al. (1998) Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry.
|
| 29. |
Schwartz PJ et al. (1998) Prolongation of the QT interval and the sudden infant death syndrome.
|
| 30. |
Shimizu W et al. (1998) Improvement of repolarization abnormalities by a K+ channel opener in the LQT1 form of congenital long-QT syndrome.
|
| 31. |
Klein HO et al. (1996) Congenital long-QT syndrome: deleterious effect of long-term high-rate ventricular pacing and definitive treatment by cardiac transplantation.
|
| 32. |
Benhorin J et al. (1993) Evidence of genetic heterogeneity in the long QT syndrome.
|
| 33. |
Curran M et al. (1993) Locus heterogeneity of autosomal dominant long QT syndrome.
|
| 34. |
Pacia SV et al. (1994) The prolonged QT syndrome presenting as epilepsy: a report of two cases and literature review.
|
| 35. |
Millat G et al. (2006) Spectrum of pathogenic mutations and associated polymorphisms in a cohort of 44 unrelated patients with long QT syndrome.
|
| 36. |
Imboden M et al. (2006) Female predominance and transmission distortion in the long-QT syndrome.
|
| 37. |
Napolitano C et al. (2005) Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice.
|
| 38. |
Priori SG et al. (1999) Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III.
|
| 39. |
Priori SG et al. (1999) Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II.
|
| 40. |
Ackerman MJ et al. (1998) A novel mutation in KVLQT1 is the molecular basis of inherited long QT syndrome in a near-drowning patient's family.
|
| 41. |
Priori SG et al. (1998) A recessive variant of the Romano-Ward long-QT syndrome?
|
| 42. |
Russell MW et al. (1996) KVLQT1 mutations in three families with familial or sporadic long QT syndrome.
|
| 43. |
Wang Q et al. (1996) Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias.
|
| 44. |
None (1986) The heart rate of Romano-Ward syndrome patients.
|
| 45. |
Tester DJ et al. (2005) Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing.
|
| 46. |
Westenskow P et al. (2004) Compound mutations: a common cause of severe long-QT syndrome.
|
| 47. |
Yang P et al. (2002) Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes.
|
| 48. |
Splawski I et al. (2000) Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2.
|
| 49. |
Jongbloed RJ et al. (1999) Novel KCNQ1 and HERG missense mutations in Dutch long-QT families.
|
| 50. |
Berthet M et al. (1999) C-terminal HERG mutations: the role of hypokalemia and a KCNQ1-associated mutation in cardiac event occurrence.
|
| 51. |
Zareba W et al. (1998) Influence of genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group.
|
| 53. |
Gale GE et al. (1970) Hereditary prolongation of QT interval . Study of two families.
|
| 54. |
Horn CA et al. (1986) The congenital long QT syndrome. An unusual cause of childhood seizures.
|
| 55. |
Moss AJ et al. (1991) The long QT syndrome. Prospective longitudinal study of 328 families.
|
| 56. |
Keating M et al. (1991) Consistent linkage of the long-QT syndrome to the Harvey ras-1 locus on chromosome 11.
|
| 57. |
Göhl K et al. (1991) Congenital myocardial sympathetic dysinnervation (CMSD)--a structural defect of idiopathic long QT syndrome.
|
| 58. |
Keating M et al. (1991) Linkage of a cardiac arrhythmia, the long QT syndrome, and the Harvey ras-1 gene.
|
| 59. |
Vincent GM et al. (1992) The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome.
|
| 60. |
Furberg C et al. (1975) Familial qt prolongation and risk of sudden death.
|
| 61. |
Roy PR et al. (1976) Hereditary prolongation of the Q-T interval. Genetic observations and management in three families with twelve affected members.
|
| 62. |
Kukolich MK et al. (1977) Sudden infant death syndrome: normal QT interval on ECGs of relatives.
|
| 63. |
None (1978) Hereditary QT prolongation syndrome in Japan: genetic analysis and pathological findings of the conducting system.
|
| 64. |
Moss AJ et al. (1979) Sudden death and the idiopathic long Q-T syndrome.
|
| 65. |
Pony JC et al. (1977) [Familial long QT-syncope syndrome. 2 cases of Romano-Ward syndrome].
|
| 66. |
Baudouy P et al. (1977) [Romano-Ward syndrome and left stellectomy. General review apropos of a recent case].
|
| 67. |
None (1976) Cardiac sympathetic innervation and the sudden infant death syndrome. A possible pathogenetic link.
|
| 68. |
Johnson JN et al. (2008) Prevalence of early-onset atrial fibrillation in congenital long QT syndrome.
|
| 69. |
OMIM.ORG article Omim 192500
|