Immunodeficiency 38

Immunodeficiency 38 is an autosomal recessive disorder caused by mutations of the ISG15 gene which is predominantly characterized by a susceptibility to mycobacterial infections.

Systematic

Primary immunodeficiency
	Achondroplasia-SCID syndrome
	Autoinflammation, antibody deficiency, and immune dysregulation syndrome
	Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome
	Disposition to infections
	IRAK4 deficiency
	Immunodeficiency 20
	Immunodeficiency 21
	Immunodeficiency 31A
	Immunodeficiency 31B
	Immunodeficiency 31C
	Immunodeficiency 33
	Immunodeficiency 38
		ISG15
	Immunodeficiency 41
	Immunodeficiency 51
	Immunodeficiency 68
	Immunodeficiency 69
	Immunodeficiency 74, COVID19-related
	Immunodeficiency-centromeric instability-facial anomalies syndrome
	Variable immunodeficiency type 7
	Vasculitis due to ADA2 deficiency
	Wiskott–Aldrich syndrome

References:

1.	Bogunovic D et al. (2012) Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency.

2.	Zhang X et al. (2015) Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation.

Update: June 23, 2025

Copyright © 2005-2025 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits