Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The gene KLF11 encodes a zinc finger transcription factor involved in regulation of insulin secretetion. Missensemutations in this gene might cause autosomal dominant MODY7 diabetes.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Multiplex Ligation-Dependent Probe Amplification |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Neve B et al. (2005) Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. 
|
| 2. |
NCBI article NCBI 8462
|
| 3. |
OMIM.ORG article Omim 603301
|
| 4. |
Orphanet article Orphanet ID 122868
|
| 5. |
Wikipedia article Wikipedia EN (KLF11)
|
 |
Copyright © 2005-2025 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944 Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits |
