Zinc finger protein GLIS2
The gene GLIS2 encodes a transcription factor. Mutations in this gene are associated with autosomal recessive ciliopathy nephronophthisis 7.
Halbritter J et al. (2013) Identification of 99 novel mutations in a worldwide cohort of 1,056 patients with a nephronophthisis-related ciliopathy.
Attanasio M et al. (2007) Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis.
Zhang F et al. (2001) Genomic structure of the gene encoding the human GLI-related, Krüppel-like zinc finger protein GLIS2.
Zhang F et al. (2002) Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis.
Orphanet ID 168309
Wikipedia EN (GLIS2)
Update: Aug. 14, 2020