Optineurin

Li X et al. (2008) A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease.

Lazarou M et al. (2015) The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.

Pottier C et al. (2015) Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.

Vaibhava V et al. (2012) Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17.

Deng HX et al. (2011) Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations.

Wild P et al. (2011) Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.

Maruyama H et al. (2010) Mutations of optineurin in amyotrophic lateral sclerosis.

Chi ZL et al. (2010) Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice.

Morton S et al. (2008) Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma.

Park BC et al. (2007) Interaction between two glaucoma genes, optineurin and myocilin.

Tang S et al. (2003) The association between Japanese primary open-angle glaucoma and normal tension glaucoma patients and the optineurin gene.

Vittitow J et al. (2002) Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure.

Hattula K et al. () FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis.

Schwamborn K et al. (2000) Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway.

Moreland RJ et al. (2000) Identification of a transcription factor IIIA-interacting protein.

Faber PW et al. (1998) Huntingtin interacts with a family of WW domain proteins.

Li Y et al. (1998) Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains.

Chalasani ML et al. (2007) A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

Rezaie T et al. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin.

Sarfarazi M et al. (1998) Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region.

Funayama T et al. (2004) Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma.

Orphanet article

NCBI article

OMIM.ORG article

Wikipedia article