TRAF3 Interacting Protein 2

Morelli C et al. (2000) Cloning and characterization of two overlapping genes in a subregion at 6q21 involved in replicative senescence and schizophrenia.

Li X et al. (2000) Act1, an NF-kappa B-activating protein.

Leonardi A et al. (2000) CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.

Pacifico F et al. (2003) Promoter identification of CIKS, a novel NF-kappaB activating gene, and regulation of its expression.

Qian Y et al. (2007) The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

Matsushima Y et al. (2010) An atopic dermatitis-like skin disease with hyper-IgE-emia develops in mice carrying a spontaneous recessive point mutation in the Traf3ip2 (Act1/CIKS) gene.

Hüffmeier U et al. (2010) Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.

Ellinghaus E et al. (2010) Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

Sønder SU et al. (2012) CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.

Zhang B et al. (2013) Crystal structure of IL-17 receptor B SEFIR domain.

Boisson B et al. (2013) An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.