Hereditary FSGS type 7 is an autosomal dominant disorder caused by mutations of the PAX2 gene. As PAX2 is also responsible for papillorenal syndrome some clinical feature can overlap.
Proteinuria | |
Proteinuria, which may reach nephrotic range, is an important feature of FSGS caused by mutations of the PAX2 gene. |
1. |
Barua M et al. (2014) Mutations in PAX2 associate with adult-onset FSGS. |
2. |
OMIM.ORG article Omim 616002 |