Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Noninsulin-dependent diabetes mellitus can be caused by various gene mutations. The disease caused by CAPN10 mutations is a separate subgroup.
| 1. |
Horikawa Y et al. (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. 
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| 2. |
Hanis CL et al. (1996) A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.
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| 3. |
Altshuler D et al. (2000) Guilt by association.
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| 4. |
None (2001) Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene.
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| 5. |
Kang ES et al. (2006) A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes.
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| 6. |
Ghosh S et al. (1998) A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter.
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| 7. |
Cox NJ et al. (1999) Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.
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| 8. |
Busfield F et al. (2002) A genomewide search for type 2 diabetes-susceptibility genes in indigenous Australians.
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| 9. |
OMIM.ORG article Omim 601283
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