Hereditary non-medullary thyroid cancer 1 is an autosomal dominant disorder caused by mutations of the NKX2-1 gene.
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Klugbauer S et al. (1999) The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas. |
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Jendrzejewski J et al. (2012) The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. |
21. |
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30. |
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31. |
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33. |
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34. |
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35. |
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43. |
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45. |
Learoyd DL et al. (1998) RET/PTC and RET tyrosine kinase expression in adult papillary thyroid carcinomas. |
46. |
Sugg SL et al. (1998) Distinct multiple RET/PTC gene rearrangements in multifocal papillary thyroid neoplasia. |
47. |
Canzian F et al. (1998) A gene predisposing to familial thyroid tumors with cell oxyphilia maps to chromosome 19p13.2. |
48. |
Lesueur F et al. (1999) Genetic heterogeneity in familial nonmedullary thyroid carcinoma: exclusion of linkage to RET, MNG1, and TCO in 56 families. NMTC Consortium. |
49. |
Trovato M et al. (1999) Loss of heterozygosity of the long arm of chromosome 7 in follicular and anaplastic thyroid cancer, but not in papillary thyroid cancer. |
51. |
Fenton CL et al. (2000) The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults. |
52. |
Chua EL et al. (2000) Prevalence and distribution of ret/ptc 1, 2, and 3 in papillary thyroid carcinoma in New Caledonia and Australia. |
53. |
Corvi R et al. (2000) RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma. |
54. |
Klein M et al. (2001) Increased expression of the vascular endothelial growth factor is a pejorative prognosis marker in papillary thyroid carcinoma. |
55. |
Hrafnkelsson J et al. (2001) Familial non-medullary thyroid cancer in Iceland. |
56. |
Elisei R et al. (2001) RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults. |
57. |
Kitamura Y et al. (2001) Allelotyping of follicular thyroid carcinoma: frequent allelic losses in chromosome arms 7q, 11p, and 22q. |
58. |
Mechler C et al. (2001) Papillary thyroid carcinoma: 6 cases from 2 families with associated lymphocytic thyroiditis harbouring RET/PTC rearrangements. |
59. |
Savagner F et al. (2002) Analysis of Tg transcripts by real-time RT-PCR in the blood of thyroid cancer patients. |
60. |
Finn SP et al. (2003) Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma. |
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OMIM.ORG article Omim 188550 |