
Hereditary non-medullary thyroid cancer 1 is an autosomal dominant disorder caused by mutations of the NKX2-1 gene.
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| 3. | Kimura ET et al. (2003) High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.   | 
| 4. | Carlomagno F et al. (2003) Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).   | 
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| 11. | García-Rostán G et al. (2005) Mutation of the PIK3CA gene in anaplastic thyroid cancer.   | 
| 12. | Zhu Z et al. (2006) Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity.   | 
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| 16. | Klugbauer S et al. (1999) The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas.   | 
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| 20. | Jendrzejewski J et al. (2012) The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.   | 
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| 25. | Phade VR et al. (1981) Familial papillary carcinoma of the thyroid.   | 
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| 28. | Herrmann MA et al. (1991) Cytogenetic and molecular genetic studies of follicular and papillary thyroid cancers.   | 
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| 30. | Perkel VS et al. (1988) Radiation-induced thyroid neoplasms: evidence for familial susceptibility factors.   | 
| 31. | Carlomagno F et al. (2002) The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes.   | 
| 32. | Klugbauer S et al. (1998) Detection of a novel type of RET rearrangement (PTC5) in thyroid carcinomas after Chernobyl and analysis of the involved RET-fused gene RFG5.   | 
| 33. | Pierotti MA et al. (1992) Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.   | 
| 34. | Santoro M et al. (1992) Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.   | 
| 35. | Nikiforova MN et al. (2003) RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.   | 
| 36. | Dwight T et al. (2003) Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.   | 
| 37. | Kroll TG et al. (2000) PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected].   | 
| 38. | Ngan ES et al. (2009) A germline mutation (A339V) in thyroid transcription factor-1 (TITF-1/NKX2.1) in patients with multinodular goiter and papillary thyroid carcinoma.   | 
| 39. | Fortunati N et al. (2004) Valproic acid induces the expression of the Na+/I- symporter and iodine uptake in poorly differentiated thyroid cancer cells.   | 
| 40. | Bongarzone I et al. (1994) Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas.   | 
| 41. | Takami H et al. (1996) Familial nonmedullary thyroid cancer: an emerging entity that warrants aggressive treatment.   | 
| 42. | Burgess JR et al. (1997) Two families with an autosomal dominant inheritance pattern for papillary carcinoma of the thyroid.   | 
| 43. | Pierotti MA et al. (1996) Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells.   | 
| 45. | Learoyd DL et al. (1998) RET/PTC and RET tyrosine kinase expression in adult papillary thyroid carcinomas.   | 
| 46. | Sugg SL et al. (1998) Distinct multiple RET/PTC gene rearrangements in multifocal papillary thyroid neoplasia.   | 
| 47. | Canzian F et al. (1998) A gene predisposing to familial thyroid tumors with cell oxyphilia maps to chromosome 19p13.2.   | 
| 48. | Lesueur F et al. (1999) Genetic heterogeneity in familial nonmedullary thyroid carcinoma: exclusion of linkage to RET, MNG1, and TCO in 56 families. NMTC Consortium.   | 
| 49. | Trovato M et al. (1999) Loss of heterozygosity of the long arm of chromosome 7 in follicular and anaplastic thyroid cancer, but not in papillary thyroid cancer.   | 
| 51. | Fenton CL et al. (2000) The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults.   | 
| 52. | Chua EL et al. (2000) Prevalence and distribution of ret/ptc 1, 2, and 3 in papillary thyroid carcinoma in New Caledonia and Australia.   | 
| 53. | Corvi R et al. (2000) RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma.   | 
| 54. | Klein M et al. (2001) Increased expression of the vascular endothelial growth factor is a pejorative prognosis marker in papillary thyroid carcinoma.   | 
| 55. | Hrafnkelsson J et al. (2001) Familial non-medullary thyroid cancer in Iceland.   | 
| 56. | Elisei R et al. (2001) RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults.   | 
| 57. | Kitamura Y et al. (2001) Allelotyping of follicular thyroid carcinoma: frequent allelic losses in chromosome arms 7q, 11p, and 22q.   | 
| 58. | Mechler C et al. (2001) Papillary thyroid carcinoma: 6 cases from 2 families with associated lymphocytic thyroiditis harbouring RET/PTC rearrangements.   | 
| 59. | Savagner F et al. (2002) Analysis of Tg transcripts by real-time RT-PCR in the blood of thyroid cancer patients.   | 
| 60. | Finn SP et al. (2003) Ret/PTC chimeric transcripts in an Irish cohort of sporadic papillary thyroid carcinoma.   | 
| 61. | OMIM.ORG articleOmim 188550   |