Susceptibility to salt-sensitive essential hypertension is associated with genetic variations.
![]() |
||||
![]() |
![]() ![]() |
|||
![]() |
![]() ![]() |
|||
![]() |
![]() ![]() |
|||
![]() |
![]() |
|||
![]() |
![]() |
|||
![]() |
![]() |
|||
![]() |
![]() |
|||
![]() |
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
|||
![]() |
![]() |
![]() |
![]() |
![]() |
1. |
None (1996) Molecular genetics of human blood pressure variation. ![]() |
2. |
Xu X et al. (1999) An extreme-sib-pair genome scan for genes regulating blood pressure. ![]() |
3. |
Siffert W et al. (1998) Association of a human G-protein beta3 subunit variant with hypertension. ![]() |
4. |
Tanaka M et al. (1997) Genetically determined chloride-sensitive hypertension and stroke. ![]() |
5. |
Vincent M et al. (1997) A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist. ![]() |
6. |
Churchill PC et al. (1997) Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer. ![]() |
7. |
Chiang FT et al. (1997) Association of the renin gene polymorphism with essential hypertension in a Chinese population. ![]() |
8. |
Noon JP et al. (1997) Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. ![]() |
9. |
Pietruck F et al. (1996) Selectively enhanced cellular signaling by Gi proteins in essential hypertension. G alpha i2, G alpha i3, G beta 1, and G beta 2 are not mutated. ![]() |
10. |
Frossard PM et al. (1995) Association between a dimorphic site on chromosome 12 and clinical diagnosis of hypertension in three independent populations. ![]() |
11. |
Wu DA et al. (1996) Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. ![]() |
12. |
Baima J et al. (1999) Evidence for linkage between essential hypertension and a putative locus on human chromosome 17. ![]() |
13. |
Gu L et al. (1996) Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1. ![]() |
14. |
Brown DM et al. (1996) Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. ![]() |
15. |
Kurtz TW et al. (1993) Genetics of essential hypertension. ![]() |
16. |
Edwards CR et al. (1993) Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? ![]() |
17. |
Benediktsson R et al. (1993) Glucocorticoid exposure in utero: new model for adult hypertension. ![]() |
18. |
Deng AY et al. (1994) Mapping of a quantitative trait locus for blood pressure on rat chromosome 2. ![]() |
19. |
Dubay C et al. (1993) Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. ![]() |
20. |
Cicila GT et al. (1993) Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. ![]() |
21. |
Siffert W et al. (1995) Enhanced G protein activation in immortalized lymphoblasts from patients with essential hypertension. ![]() |
22. |
Kreutz R et al. (1995) Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10. ![]() |
23. |
None (1963) Heredity in hypertension. ![]() |
24. |
Deo RC et al. (2007) A high-density admixture scan in 1,670 African Americans with hypertension. ![]() |
25. |
Rutherford S et al. (2007) A chromosome 11q quantitative-trait locus influences change of blood-pressure measurements over time in Mexican Americans of the San Antonio Family Heart Study. ![]() |
26. |
Chang YP et al. (2007) Multiple genes for essential-hypertension susceptibility on chromosome 1q. ![]() |
27. |
Guzmán B et al. (2006) Implication of chromosome 18 in hypertension by sibling pair and association analyses: putative involvement of the RKHD2 gene. ![]() |
28. |
Wallace C et al. (2006) Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. ![]() |
29. |
Zhu X et al. (2005) Admixture mapping for hypertension loci with genome-scan markers. ![]() |
30. |
Gainer JV et al. (2005) Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. ![]() |
31. |
Koivukoski L et al. (2004) Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3. ![]() |
32. |
Rutherford S et al. (2004) Sibpair studies implicate chromosome 18 in essential hypertension. ![]() |
33. |
MCDONOUGH JR et al. (1964) BLOOD PRESSURE AND HYPERTENSIVE DISEASE AMONG NEGROES AND WHITES; A STUDY IN EVANS COUNTY, GEORGIA. ![]() |
34. |
Bonnardeaux A et al. (1994) Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. ![]() |
35. |
DAHL LK et al. (1962) Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension. ![]() |
36. |
Funke-Kaiser H et al. (2003) Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation. ![]() |
37. |
Nakayama T et al. (2002) Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension. ![]() |
38. |
Angius A et al. (2002) A new essential hypertension susceptibility locus on chromosome 2p24-p25, detected by genomewide search. ![]() |
39. |
Yamamoto N et al. (2002) Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension. ![]() |
40. |
Rutherford S et al. (2001) Chromosome 17 and the inducible nitric oxide synthase gene in human essential hypertension. ![]() |
41. |
Lifton RP et al. (2001) Molecular mechanisms of human hypertension. ![]() |
42. |
Glenn CL et al. (2000) Linkage and association of tumor necrosis factor receptor 2 locus with hypertension, hypercholesterolemia and plasma shed receptor. ![]() |
43. |
Garbers DL et al. (1999) The molecular basis of hypertension. ![]() |
44. |
Garay RP et al. (1979) A new test showing abnormal net Na+ and K+ fluxes in erythrocytes of essential hypertensive patients. ![]() |
45. |
None (1990) Inheritance of hypertension and blood pressure reactivity. ![]() |
46. |
Ravogli A et al. (1990) Early 24-hour blood pressure elevation in normotensive subjects with parental hypertension. ![]() |
47. |
Pérusse L et al. (1991) Evidence that a single gene with gender- and age-dependent effects influences systolic blood pressure determination in a population-based sample. ![]() |
48. |
None (1991) Blood pressure control--special role of the kidneys and body fluids. ![]() |
49. |
Rebbeck TR et al. (1991) Genetic and environmental explanations for the distribution of sodium-lithium countertransport in pedigrees from Rochester, MN. ![]() |
50. |
Lifton RP et al. (1991) Exclusion of the Na(+)-H+ antiporter as a candidate gene in human essential hypertension. ![]() |
51. |
Parmer RJ et al. (1992) Baroreflex sensitivity and heredity in essential hypertension. ![]() |
52. |
Hilbert P et al. (1991) Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats. ![]() |
53. |
Jacob HJ et al. (1991) Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. ![]() |
54. |
None (1978) Normotension and hypertension: the mysterious viability of the false. ![]() |
55. |
Trippodo NC et al. (1981) Similarities of genetic (spontaneous) hypertension. Man and rat. ![]() |
56. |
Gong M et al. (2003) Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p. ![]() |
57. |
Dong N et al. (2013) Corin mutation R539C from hypertensive patients impairs zymogen activation and generates an inactive alternative ectodomain fragment. ![]() |
58. |
Wang W et al. (2008) Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity. ![]() |
59. |
Dries DL et al. (2005) Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. ![]() |
60. |
Machnik A et al. (2009) Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. ![]() |
61. |
Rapp JP et al. (1989) A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. ![]() |
62. |
van Hooft IM et al. (1991) Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents. ![]() |
63. |
Zhang Y et al. (2004) D919G polymorphism of methionine synthase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients. ![]() |
64. |
Julier C et al. (1997) Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. ![]() |
65. |
Caulfield M et al. (1994) Linkage of the angiotensinogen gene to essential hypertension. ![]() |
66. |
None (1985) MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party. ![]() |
67. |
None (1995) Heterogeneous hypertension. ![]() |
68. |
None (1980) Hypertension and the red cell. ![]() |
69. |
Canessa M et al. (1980) Increased sodium-lithium countertransport in red cells of patients with essential hypertension. ![]() |
70. |
Garay RP et al. (1980) Laboratory distinction between essential and secondary hypertension by measurement of erythrocyte cation fluxes. ![]() |
71. |
Ibsen KK et al. () Essential hypertension: sodium-lithium countertransport in erythrocytes from patients and from children having one hypertensive parent. ![]() |
72. |
Etkin NL et al. (1982) Racial differences in hypertension-associated red cell sodium permeability. ![]() |
73. |
Woods JW et al. (1982) Increased red-cell sodium-lithium countertransport in normotensive sons of hypertensive parents. ![]() |
74. |
Woods JW et al. (1983) Perturbation of sodium-lithium countertransport in red cells. ![]() |
75. |
Woods KL et al. (1981) Familial abnormality of erythrocyte cation transport in essential hypertension. ![]() |
76. |
De Mendonca M et al. (1980) Abnormal net Na+ and K+ fluxes in erythrocytes of three varieties of genetically hypertensive rats. ![]() |
77. |
Garay RP et al. (1980) Inherited defect in a Na+, K-co-transport system in erythrocytes from essential hypertensive patients. ![]() |
78. |
None (1983) Genetics, environment, and hypertension. ![]() |
79. |
Clegg G et al. (1982) The heterogeneity of essential hypertension. Relation between lithium efflux and sodium content of erythrocytes and a family history of hypertension. ![]() |
80. |
de Wardener HE et al. (1982) The natriuretic hormone and essential hypertension. ![]() |
81. |
Parfrey PS et al. (1981) Blood pressure and hormonal changes following alteration in dietary sodium and potassium in young men with and without a familial predisposition to hypertension. ![]() |
82. |
Kurtz TW et al. (1985) Hypertension in the recently weaned Dahl salt-sensitive rat despite a diet deficient in sodium chloride. ![]() |
83. |
None (1986) Red-cell lithium-sodium countertransport and renal lithium clearance in hypertension. ![]() |
84. |
Hasstedt SJ et al. (1988) The inheritance of intraerythrocytic sodium level. ![]() |
85. |
Hasstedt SJ et al. (1988) Hypertension and sodium-lithium countertransport in Utah pedigrees: evidence for major-locus inheritance. ![]() |
86. |
Kagamimori S et al. (1985) Familial aggregation of red blood cell cation transport systems in Japanese families. ![]() |
87. |
OMIM.ORG article Omim 145500![]() |