Psoriasis susceptibility 1

Balendran N et al. (1999) Characterization of the major susceptibility region for psoriasis at chromosome 6p21.3.

Asumalahti K et al. (2002) Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.

Reich K et al. (2002) Promoter polymorphisms of the genes encoding tumor necrosis factor-alpha and interleukin-1beta are associated with different subtypes of psoriasis characterized by early and late disease onset.

Gudjónsson JE et al. (2002) HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features.

Schmitt-Egenolf M et al. (2001) Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families.

O'Brien KP et al. (2001) The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene.

Mallon E et al. (2000) HLA-C and guttate psoriasis.

Gonzalez S et al. (2000) The OTF3 gene polymorphism confers susceptibility to psoriasis independent of the association of HLA-Cw*0602.

Asumalahti K et al. (2000) A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele.

Nair RP et al. (2000) Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.

Oka A et al. (1999) Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene.

Veal CD et al. (2002) Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus.

Tazi Ahnini R et al. (1999) Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis.

Leder RO et al. (1999) Psoriasis linkage in the HLA region.

Leder RO et al. () Familial psoriasis and HLA-B: unambiguous support for linkage in 97 published families.

Jenisch S et al. (1998) Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region.

Burden AD et al. (1998) Genetics of psoriasis: paternal inheritance and a locus on chromosome 6p.

Swanbeck G et al. (1997) Genetic counselling in psoriasis: empirical data on psoriasis among first-degree relatives of 3095 psoriatic probands.

Trembath RC et al. (1997) Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis.

Schmitt-Egenolf M et al. (1996) Familial juvenile onset psoriasis is associated with the human leukocyte antigen (HLA) class I side of the extended haplotype Cw6-B57-DRB1*0701-DQA1*0201-DQB1*0303: a population- and family-based study.

Chen ML et al. (1996) Induction of vitamin D receptor mRNA expression in psoriatic plaques correlates with clinical response to 1,25-dihydroxyvitamin D3.

Lowes MA et al. (2005) Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).

Kopp T et al. (2015) Clinical improvement in psoriasis with specific targeting of interleukin-23.

Tonel G et al. (2010) Cutting edge: A critical functional role for IL-23 in psoriasis.

et al. (2010) A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Nestle FO et al. (2009) Psoriasis.

Li Y et al. (2009) Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22.

Hollox EJ et al. (2008) Psoriasis is associated with increased beta-defensin genomic copy number.

Lande R et al. (2007) Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.

Conrad C et al. (2007) Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

Krueger GG et al. (2007) A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis.

Rosbotham JL et al. (1994) An association between psoriasis and hereditary multiple exostoses. A clue for the mapping of a psoriasis susceptibility gene?

Helms C et al. (2005) Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR.

Orrù S et al. (2005) Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN).

Elomaa O et al. (2004) Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.

STEINBERG AG et al. (1951) A genetic and statistical study of psoriasis.

ABELE DC et al. (1963) HEREDITY AND PSORIASIS. STUDY OF A LARGE FAMILY.

WARD JH et al. (1961) Inheritance of psoriasis in a Utah kindred.

STEINBERG AG et al. (1952) A further note on the genetics of psoriasis.

Asumalahti K et al. (2003) Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.

Gudjonsson JE et al. (2003) Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes.

Nair RP et al. (1997) Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan.

None (2003) The International Psoriasis Genetics Study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs.

Veal CD et al. (2001) Identification of a novel psoriasis susceptibility locus at 1p and evidence of epistasis between PSORS1 and candidate loci.

Hüffmeier U et al. (2009) Characterisation of psoriasis susceptibility locus 6 (PSORS6) in patients with early onset psoriasis and evidence for interaction with PSORS1.

Caruso R et al. (2009) Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis.

Matthews D et al. (1996) Evidence that a locus for familial psoriasis maps to chromosome 4q.

Zenz R et al. (2005) Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.

Capon F et al. (1999) Evidence for interaction between psoriasis-susceptibility loci on chromosomes 6p21 and 1q21.

Enlund F et al. (1999) Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q.

Park BS et al. (1999) Vitamin D receptor polymorphism is associated with psoriasis.

Jordan CT et al. (2012) Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

Zhang XJ et al. (2002) Evidence for a major psoriasis susceptibility locus at 6p21(PSORS1) and a novel candidate region at 4q31 by genome-wide scan in Chinese hans.

Sugiura K et al. (2013) The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.

Setta-Kaffetzi N et al. (2013) Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated pustular phenotypes.

Marrakchi S et al. (2011) Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis.

Boyman O et al. (2004) Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha.

Ghoreschi K et al. (2003) Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease.

Nair RP et al. (2006) Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.

Asadullah K et al. (2001) Interleukin-10 promoter polymorphism in psoriasis.

Abrams JR et al. (1999) CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.

Sayegh MH et al. (1998) The role of T-cell costimulatory activation pathways in transplant rejection.

Farber EM et al. (1974) Natural history of psoriasis in 61 twin pairs.

Swanbeck G et al. (1994) A population genetic study of psoriasis.

Bata-Csorgo Z et al. (1995) Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes.

Tiilikainen A et al. (1980) Psoriasis and HLA-Cw6.

Burch PR et al. (1981) Mode of inheritance in psoriasis.

Pietrzyk JJ et al. (1982) Family studies in psoriasis. I. Complex segregation analysis.

Brandrup F et al. (1982) Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution.

Watson W et al. (1972) The genetics of psoriasis.

White SH et al. (1972) Disturbance of HL-A antigen frequency in Psoriasis.

Russell TJ et al. (1972) Histocompatibility (HL-A) antigens associated with psoriasis.

Reiser H et al. (1996) Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases.

Moll JM et al. (1973) Familial occurrence of psoriatic arthritis.

Beckman L et al. (1974) HL-A antigens, blood groups, serum groups and red cell enzyme thypes in psoriasis.

Kimberling W et al. (1973) The inheritance of psoriasis.

Burch PR et al. (1965) Psoriasis: aetiological aspects.

Propping P et al. (1985) Increased birth weight in psoriasis--another expression of a "thrifty genotype"?

Saiag P et al. (1985) Psoriatic fibroblasts induce hyperproliferation of normal keratinocytes in a skin equivalent model in vitro.

Suarez-Almazor ME et al. (1990) The genetics of psoriasis. Haplotype sharing in siblings with the disease.

None (1991) Somatic recombination may explain linear psoriasis.

Chang EY et al. (1992) T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal, epidermis.