Psoriasis is quite heritable. It is associated with various loci throughout the genome. The type 5 susceptibility is associates with 3q21.
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Enlund F et al. () Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden.
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| 2. |
Hewett D et al. (2002) Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.
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| 3. |
Samuelsson L et al. (2004) Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5.
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| 4. |
Hüffmeier U et al. (2005) Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris.
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| 5. |
Vasilopoulos Y et al. (2008) Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.
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