Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The ANGPTL8 gene encodes an inhibitor of lipolysis. Therefore it is a probably candidate for mutation in hypertriglyceridemia.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
Combined familial hyperlipidemia with dysfunctional VLDL metabolism
|
|||
|
ANGPTL8
|
||
|
|
APOA1
|
||
|
|
APOA4
|
||
|
|
APOA5
|
||
|
|
APOC3
|
||
|
|
CETP
|
||
|
|
GALNT2
|
||
|
|
LCAT
|
||
|
|
LIPC
|
||
|
|
LIPG
|
||
|
|
LPL
|
||
|
|
RXRG
|
||
|
USF1
|
||
|
|
|
|
| 1. |
Cefalù AB et al. () Identification of a novel LMF1 nonsense mutation responsible for severe hypertriglyceridemia by targeted next-generation sequencing. 
|
| 2. |
None (2012) Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels.
|
| 3. |
Quagliarini F et al. (2012) Atypical angiopoietin-like protein that regulates ANGPTL3.
|
| 4. |
Tseng YH et al. (2014) Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism.
|
| 5. |
Gusarova V et al. (2014) ANGPTL8/betatrophin does not control pancreatic beta cell expansion.
|
| 6. |
NCBI article NCBI 55908
|
| 7. |
OMIM.ORG article Omim 616223
|
| 8. |
Wikipedia article Wikipedia EN (ANGPTL8)
|
 |
Copyright © 2005-2025 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944 Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits |