The disposition to develop inflammatory bowel disease is hereditary. Various genes are responsible.
1. |
Grant B et al. (1996) The Caenorhabditis elegans sel-1 gene, a negative regulator of lin-12 and glp-1, encodes a predicted extracellular protein. |
2. |
Grant B et al. (1997) Structure, function, and expression of SEL-1, a negative regulator of LIN-12 and GLP-1 in C. elegans. |
3. |
Biunno I et al. (1997) Isolation of a pancreas-specific gene located on human chromosome 14q31: expression analysis in human pancreatic ductal carcinomas. |
4. |
Donoviel DB et al. (1999) SEL-1L maps to human chromosome 14, near the insulin-dependent diabetes mellitus locus 11. |
5. |
Harada Y et al. (1999) Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1. |
6. |
Cattaneo M et al. (2004) Identification of a region within SEL1L protein required for tumour growth inhibition. |
7. |
Odom DT et al. (2007) Tissue-specific transcriptional regulation has diverged significantly between human and mouse. |
8. |
Kaneko M et al. (2007) A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes. |
9. |
Mueller B et al. (2008) SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins. |
10. |
Francisco AB et al. (2011) Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia. |
11. |
Sun S et al. (2016) Epithelial Sel1L is required for the maintenance of intestinal homeostasis. |
12. |
Orphanet article Orphanet ID 238569 |
13. |
Wikipedia article Wikipedia EN (Inflammatory_bowel_disease) |