Complement factor H-related 2
This is one of 5 complement factor H-related genes that occur in tandem with CFH. All these genes though less transcribed share some structural domains and functional properties with complement factor H. Some mutations and polymorphisms have been associated with atypical HUS and age-related macula degeneration.
Genetests:
Related Diseases:
References:
1. |
Nürnberger J et al. (2009) Eculizumab for atypical hemolytic-uremic syndrome.
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2. |
Zhang H et al. (2008) The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.
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3. |
NCBI article
NCBI 3080
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4. |
OMIM.ORG article
Omim 600889
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5. |
Wikipedia article
Wikipedia EN (CFHR2)
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Update: Aug. 14, 2020